Do you ever change your CNS radiation recommendations for patients with multiple sclerosis (MS)?

Topics: Radiation Oncology • Neuro-Oncology

Would you ever defer radiation in patients with primary brain tumors or would you manage these patients similarly to non-MS patients? How do you counsel MS patients regarding their risks?

At least one small series of 15 consecutive patients from Mayo suggested an increase in severe toxicity with older, large-field radiation (Miller, Robert C., et al. "Multiple sclerosis, brain radiotherapy, and risk of neurotoxicity: the Mayo Clinic experience." International Journal of Radiation Oncology• Biology• Physics 66.4 (2006): 1178-1186.

Answer from: Radiation Oncologist at Academic Institution

I will counsel patients with MS about potential increased radiation-induced toxicity for intracranial radiotherapy. As the publication states, the techniques used may not be comparable to modern techniques. I don't routinely defer radiotherapy simply because a patient has MS and would have a convers...

Comments

Radiation Oncologist at Florida International University
I agree with @Tony J. Wang; in spite of the small ...

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