Do you ever stop pertuzumab for stable disease in a patient with metastatic, HER2 positive breast with stable disease?

I would only stop pertuzumab if there is considerable toxicity (rashes, diarrhea, severe infusion reactions, etc). Given the substantial overall survival benefit seen in the CLEOPATRA study, I make every effort to continue both trastuzumab and pertuzumab in patients with metastatic HER2+ breast canc...

I never stop unless the patient has toxicity or progression, even if you give it for years.