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Do you ever taper or stop urate lowering therapy in patients who have had no gout flares and serum urate persistently below 6 mg/dl?

In patients with CKD, does urate lowering therapy have an effect (positive or negative) on progression of CKD?
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Do you ever taper or stop urate lowering therapy in patients who have had no gout flares?

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1 Answer
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Rheumatology · National institues of Health
Answered on

Part 1: Yes, but not often.

Part 2: No, or extremely rarely.

Read on.

Urate lowering therapy (ULT) mobilizes monosodium urate (MSU) deposits and in time will resolve all of the clinical features of gout. The formation of these deposits results from sustained serum uric acid (SUA) elevations in excess...

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