Do you ever taper or stop urate lowering therapy in patients who have had no gout flares and serum urate persistently below 6 mg/dl?

Topics: Rheumatology • Crystal Arthritis • Gout

In patients with CKD, does urate lowering therapy have an effect (positive or negative) on progression of CKD?

Answer from: at Academic Institution

Part 1: Yes, but not often.Part 2: No, or extremely rarely. Read on. Urate lowering therapy (ULT) mobilizes monosodium urate (MSU) deposits and in time will resolve all of the clinical features of gout. The formation of these deposits results from sustained serum uric acid (SUA) elevations...

Comments

at Texas Tech University Health Sciences Center
The key is to keep uric acid below 6.

at Arthritis Associates
I will add that I have seen a growing number of pa...

at Uniformed Services University of the Health Sciences (USUHS)
Could someone locate an article for me? (see below...

at UTMB Health
If the hyperuricemia is mild, say 7.0 mg/dl, with ...

at NIAMS
I agree with the above, especially noting Dr. @Bar...

at George Washington University
I'd still keep the SUA at <6.0 once all clinica...

at Arthritis, Rheumatic & Bone Disease Associates
We are forgetting a very important component here....

Related Questions