When deciding on the duration of maintenance therapy, the risk of relapse, patient characteristics, and the extent of underlying organ damage will factor into the decision. In patients with a higher risk of relapse including PR3 Positive (especially if persistently positive), patients with lung/ENT...

The duration of maintenance therapy in patients with AAV depends on many factors and should be individualized. Some factors that are associated with a higher risk of relapse include PR3 positivity, seroconversion from negative to positive, ENT disease, use of a tailored approach to RTX dosing, and u...