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Do you favor ETI (Trikafta) or VTD (Alyftrek) for patients with CF eligible for either drug?

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Do you favor ETI (Trikafta) or VTD (Alyftrek) for patients with CF eligible for either drug?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Pulmonology · Hospital of the University of Pennsylvania
Answered on

For patients eligible for both medications who have not started either, I currently have equipoise; VZD appears to be slightly better in a mechanistic way (better sweat test on trials) and is once daily; however, ETI has 5.5 years of experience after approval, so we know what to expect; I suspect ov...

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