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Do you feel comfortable combining mycophenolate mofetil with azathioprine in patients with lupus?

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Rheumatology · NYU Langone Health

Aggressive immunosuppression is occasionally indicated for patients with lupus. Examples include refractory lupus nephritis, lupus with secondary CAPS, refractory immune-mediated cytopenia, etc. Treatment options often consist of high-dose steroids with at least one other immunosuppressive agent. Ad...

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Rheumatology · MUSC Health

I have not ever used that combination that I remember but certainly have had patients on mycophenolate and tacrolimus, mycophenolate and benlytsa, and mycophenolate and saphnelo. Obviously would need close follow-up regarding blood counts etc. I have also used mycophenolate along with methotrexate a...

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Rheumatology · Hackensack University Medical Center

It would be great to have a bit more information about the clinical presentation for which this combination is being considered, but I could not think of a scenario where I would consider combining MMF and Aza. In addition to the standard approaches with MMF and Belimumab or MMF/CNIs (that I would u...

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