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Do you find trabecular bone score (TBS) useful in patients with a history of ankylosing spondylitis when screening for vertebral fracture risk?

2 Answers
Mednet Member
Mednet Member
Endocrinology · Harvard Medical School
Answered on

Yes, the ankylosing spondylitis population is a group that could benefit from the evaluation of TBS. DXA-based spine bone mineral density is artificially elevated in the setting of ankylosing spondylitis (due to osteosclerotic artifact from underlying disease), and therefore, spine bone density is a...

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Mednet Member
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Rheumatology · U of AZ Phoenix Dept of Orthopaedics
Answered on

Yes, I think this could be useful. Standard DXA AP view will often be elevated due to the calcification of the ankylosing spine. We know clinically that AS may result in bone fragility and increased risk for fracture. The TBS region of interest can be limited to trabecular bone and give a reflection...

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