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How would you manage a patient with discordant TBS adjusted T-score and traditional T-score?

When a TBS-adjusted T-score suggests someone may actually be in the osteoporotic range, but the traditional T-score does not, would you treat the patient based on this additional information? This question is part of our collaboration with ACR Convergence 2025 to Continue the Conversation from the meeting. This question was inspired by the session "Updates in Osteoporosis: Where They 'Fall Short" by Dr. @Dr. First Last and Dr. @Dr. First Last. If you did not attend the meeting, information about Convergence On Demand can be found here.
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How do you integrate TBS into your fracture risk assessment?

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2 Answers
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Endocrinology · Harvard Medical School
Answered on

The ESCEO (European Society for Clinical and Economic Aspects of Osteoporosis) and IOF (International Osteoporosis Foundation) recommend the use of TBS-adjusted T-scores to help guide osteoporosis treatment decisions.

However, this recommendation is based on a single research study and therefore may...

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Nephrology · Indiana University School of Medicine
Answered on · Updated on

TBS has not been validated in CKD to predict fractures.

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