Do you generally reduce DOAC dosing for extended anticoagulation in patients with first unprovoked VTE?
Ref: EINSTEIN-CHOICE and AMPLIFY-EXT
Would you approach this differently in patients with inherited thrombophilias?
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Are you placing patients on low-intensity DOAC after treatment of first unprovoked VTE?
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1 Answer
Mednet MemberInvited Expert
Hematology · University of Wisconsin
Answered on
I frequently recommend low-intensity DOAC therapy in this setting, but only after careful consideration of the patient's risk factors for recurrent VTE and bleeding, and after determining the patient's preference about treatment options following a discussion of the pros and cons of each option.
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