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Do you generally reduce DOAC dosing for extended anticoagulation in patients with first unprovoked VTE?

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Mednet Member
Mednet Member
Hematology · University of Wisconsin

I frequently recommend low-intensity DOAC therapy in this setting, but only after careful consideration of the patient's risk factors for recurrent VTE and bleeding, and after determining the patient's preference about treatment options following a discussion of the pros and cons of each option.

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Do you generally reduce DOAC dosing for extended anticoagulation in patients with first unprovoked VTE? | Mednet