Do you give an etoposide-based regimen/more aggressive therapy for lymphoma-associated HLH, such as da-EPOCH-R over R-CHOP?
What about changing standard regimens for TCL with HLH?
Answer from: Medical Oncologist at Academic Institution
The general approach to treat the secondary lymphoma-associated HLH (LA-HLH) is to treat the underlying lymphoma- it works better in B cell lymphoma. Etoposide is probably the only agent consistently that has been shown (in several studies- mostly retrospective) to make a difference in the resolutio...
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