Do you have any advice when utilizing palliative radiation therapy in patients currently being treated with a PARP inhibitor?
Can the drug continue during radiation therapy or should it be discontinued at a specified time prior to initiation of radiation?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Yale School of Medicine
Answered on
This is an excellent question and certainly will become more of an issue with the recent FDA approval of olaparib for HR-defective (HRD) metastatic ovarian cancer. In addition, many other HRD metastatic cancers are being treated with this drug under compassionate use. Furthermore, the recent Phase I...
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