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Do you have any normal tissue constraints for endometrial cancer patients receiving EBRT and vaginal cuff brachytherapy?

1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on · Updated on

We use following constraints for EBRT

35 Gy to less than 35% of bowel bag

Rectum 40 Gy less tha 40-60%

Bladder 40 Gy less than 40-60%

Bone marrow ( pelvic bone) V20 less than 75%

Femoral heads V35 less than 5%

for brachy as adjuvant we give 5 Gy x2 to thickness of vagina

Since total dose loss limit and part if rectum and bladder to 100% or less dose

if treat for cuff recurrence then prescribe 5 Gy X 5 with multichannel cylinder to give HRCTV D90nof 75-80 Gy and limit

Rectum 2 cc to EQ2 60-65 Gy

Bladder 2cc to EQ2 65-75 Gy

‘’For extended field Kidneys V16 Gy to less than 5%

outcome data with this approach

https://www.ncbi.nlm.nih.gov/pubmed/29929925

https://www.ncbi.nlm.nih.gov/pubmed/27527897