Do you have concerns about the generalizability of MammaPrint/Oncotype testing in making chemotherapy decisions for non-Caucasian women?
For example, women of Southeast Asian descent.
Answer from: Medical Oncologist at Academic Institution
I do not have any concerns about the technical validity of these assays in non-Caucasian women. I even find the question faintly offensive; it implies that there are fundamental genetic differences between ancestry groups that are so deep that they alter the biology of their cancer.
However, socioe...
Answer from: Medical Oncologist at Academic Institution
I think the tests are generally applicable to non-Caucasian women, but should consider an “added margin of safety” in interpretation, considering racial minorities were underrepresented in some original validation studies.For women of Southeast Asian descent, data is limited. A SEER anal...