Do you integrate inhaled colistimethate sodium into existing treatment regimens for patients with bronchiectasis and PSAR infection?

I agree with Dr. @Dr. First Last. I also consider inhaled colistimethate sodium in addition to tobramycin and aztreonam when developing treatment regimens.

Of note, while the inhaled route of antibiotics can decrease the risk of side effects in other parts of the body (nephrotoxicity, ototoxicity, e...

Yes, I do integrate inhaled colistimethate sodium despite the conflicting data in the PROMIS-I and II trials. Anecdotally, I have had as much success with inhaled colistimethate as with inhaled aztreonam and inhaled tobramycin, the data for which is not robust either. I consider any of these drugs i...