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Do you offer adjuvant chemotherapy or abiraterone for patients with high and very high risk prostate cancer with still detectable PSA after radical prostatectomy and lymph node dissection?

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Do you offer adjuvant chemotherapy or abiraterone for patients with high and very high risk prostate cancer with still detectable PSA after RP and LN dissection?

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2 Answers
Mednet Member
Mednet Member
Medical Oncology · Hematology-Oncology Associates of Fredericksburg, Inc.
Answered on · Updated on

I will recommend reimaging outside conventional CT and bone scans. The goal of imaging is to rule out metastatic disease and (hopefully) identify localized residual disease in prostatectomy bed or pelvic LN and consider early salvage RT. Fluciclovine PET is now commercially available and also PSMA P...

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Mednet Member
Mednet Member
Medical Oncology · Rutgers Cancer Institute of New Jersey
Answered on

I agree with @Dr. First Last

- Advanced Imaging

- Use of early salvage therapy with ADT for 2-3 years

- No role of Docetaxel

A question occurred though, @Dr. First Last. If checking for BRCA, do you advise/recommend adjuvant PARPi?

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