Do you offer anticoagulation to patients with prior antiphospholipid antibodies detected in pregnancy without a history of pregnancy loss or thrombosis?

I do not know what the risk of pregnancy loss is in a woman without a prior history of VTE or pregnancy loss. I am sure the risk is affected by whether the woman has an underlying rheumatological disease (SLE) and whether she has single positive vs. triple positive LAC. I recommend a baby aspirin on...

Antovic et al., PMID 30364418 provided the following risk estimations: "High-risk aPL profile (LAC, triple positive, persistent moderate/high ACL in SLE) correlates with increased risk of maternal vascular thrombotic events during pregnancy (OR 12.1), pre-eclampsia (OR 2.3), APS-related pregnancy mo...

May offer baby aspirin once daily.