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Do you offer consolidative RT for patients with oligometastatic NSCLC who initially presented with a malignant pleural effusion?

Is a pleural effusion not oligometastatic by definition? The best evidence for consolidative RT was the MD Anderson/U Colorado/Western Ontario phase II trial which excluded patients with a malignant pleural effusion. https://www.ncbi.nlm.nih.gov/pubmed/27789196
1 Answer
Mednet Member
Radiation Oncology · Northeast Alabama Regional Medical Center
Answered on

You cited a very important trial. When its results were published I thought they were a real sockdolager to any continued wholesale radiotherapeutic nihilism towards asymptomatic M1 NSCLC patients. (I must admit, in training during years 1999-2003 I can't remember anyone using the word "oligometastatic" although it had been coined by that time... obviously its gaining traction now as a concept.) But if your question is "Would you irradiate a malignant pleural effusion (MPE) site in a patient who, were it not for his MPE, would be M0?" I would not. I don't think MPE is "oligometastatic by definition" either; soi-disant oligometastatic at best. There's no universally recognized oligomet definition I know of at this point. But I'd feel very co...

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