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Do you offer consolidative thoracic radiotherapy to patients with extensive stage SCLC who have a complete response to chemotherapy?

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Mednet Member
Mednet Member
Radiation Oncology · Quillen VA Medical Center

The CREST trial did not meet primary goal of improving one year survival, but it did improve 2 year OS. Looking at subset, achieving CR to chemo was an indicator of a group that "did not benefit". So the rest of the question (what volume, what dose etc) becomes irrelevant.

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Mednet Member
Mednet Member
Radiation Oncology · Cleveland Clinic

Overall, my clinical practice mirrors that of Dr. @Dr. First Last's answer based on subset analysis of the CREST trial suggesting that the patients who benefited the most were those with only a partial response in the chest, these are not full independent publications but rather information presente...

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