Do you offer hypofractionated courses of radiation with temozolomide for "elderly" patients with GBM?

The ASTRO GBM guideline states the following with regard to elderly patients:

“Given the absence of proven superiority for conventionally fractionated radiation therapy, the panel recommends hypofractionated radiation therapy for elderly patients with fair-good performance status (high quality evidence [HQE]). Temozolomide monotherapy is an efficacious alternative for elderly patients with MGMT promoter methylation (HQE), but the panel does not recommend temozolomide monotherapy as first-line the...

This question has been asked in a randomized clinical trial, "A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma" and will be presented at the ASCO Annual Meeting Plenary Session by James Perry, MD FRCPC

The results have been presented with the abstract. Basically, there is a benefit to the addition of the temozolomide and it is a reasonable option and in most circumstances, I think can ...

Yes, we do offer hypofractionated RT for elderly GBM patients off trial.