Do you perform a periodic PET CT to screen for extramedullary disease in patients with MM who are in remission?

Topics: Medical Oncology • Myeloma • NCI-CCC Tumor Board Question • Mayo Clinic • NCI-CCC Myeloma Tumor Board Question

Answer from: Medical Oncologist at Academic Institution

This is an excellent question with guidelines and inferences from clinical trials, but admittedly, no randomized data showing that surveillance PETs improve outcomes versus as-needed PETs. To start, here's what NCCN guidelines recommend for patients in surveillance/on maintenance therapy alone: "Who...

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Medical Oncologist at University of Chicago
I will second @Rahul Banerjee. I typically prefer ...

Answer from: Medical Oncologist at Community Practice

No, I don’t. The odds of finding presymptomatic EMD on a yearly scan are low and not cost-effective. We have learned in other diseases where it has been studied in clinical trials (lymphoma, breast, lung), that surveillance scans do not change outcomes. As far as I can tell, the only diseases ...

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Medical Oncologist at University of Washington, Fred Hutchinson Cancer Research Center
Agreed - I think it's a risk/benefit discussion wi...

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