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Do you prefer cinacalcet or etelcalcetide for patients with hyperparathyroidism in the setting of kidney disease?

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Have you had difficulty obtaining approval for etelcalcetide for ESKD patients with poorly controlled secondary hyperparathyroidism?

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3 Answers
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Nephrology · Premier Nephrology Medical Group
Answered on

In a group of vintage ESKD patients, assuming compliance is not an issue and hypocalcemia handled and Parsabiv utilized when approved, PTH still not controlled often. Over few thousands. The main reason is that the parathyroid hyperplasia turns to be nodular and encapsulated. And it’s time for surgi...

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Nephrology · University Of California San Francisco Medical Center At Parnassus
Answered on

Etelcalcetide has been almost impossible to get nowadays so not sure if makes a difference in what I prefer. Since it is more expensive, I am completely open to reserve etelcalcetide for cases in which cinacalcet has not worked. I believe if patients are able and take cinacalcet it works well, the p...

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Nephrology · Los Angeles Vascular Access Center
Answered on

In Davita dialysis centers, etelcalcetide (E) is difficult to prescribe unless the patient has an adverse reaction to cinacalcet (C). Before authorization, patients need to have a PTH > 800 and need to be on at least 90 mg of C either daily or three times a week.

One of the reasons for high PTH in d...

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