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Do you prescribe lower dose ICS for asthma to mitigate the risk of pneumonia in patients with a history of respiratory infections or compromised immune systems?

Do the findings from Bloom et al., PMID 39088770 influence your approach?
2 Answers
Mednet Member
Mednet MemberInvited Expert
Pulmonology · University of Alabama at Birmingham
Answered on

Yes, I do, if possible. This is based on data that demonstrates that high-dose ICS negatively impacts the microbiome diversity. While not linked directly to clinical outcomes, these findings warrant caution enough to make this simple alteration. That said, more research into the clinical impact is n...

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Mednet Member
Mednet MemberInvited Expert
Pulmonology · University of Alabama at Birmingham
Answered on

Yes i do if possible. This is based on data that demonstrates that high dose ics negatively impacts tge microbiome diversity. While not linked directky to clinical outcomes, these findings warrant caution enough to make this simple alteration. That said more research into clinical impact is needed t...

Join for free or sign in to see the full answer