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Have you used oral carbapenems to treat an outpatient with a complicated UTI caused by an ESBL-producing organism who would otherwise require hospitalization for IV carbapenem therapy, given concerns about community carbapenem stewardship?

2 Answers
Mednet Member
Mednet Member
Infectious Disease · Zucker School of Medicine at Hofstra / Northwell

To date, the only oral carbapenem that is licensed in the U.S. is tebipenem. I have no experience with this drug and would be very interested in using it when it becomes readily available.

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Mednet Member
Mednet Member
Infectious Disease · UT Southwestern School of Medicine

I have not used an oral carbepenem to treat an ESBL UTI at present. At this point, they are not used frequently, and generally when patients have a complicated UTI to the point that they are sick enough that they require a carbepenem they may need hospitalization for other reasons. Moreover, the ora...

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