Infectious Disease   

Questions discussed in this category



Do you empirically treat itchy patients -with a non specific rash- for scabies without obvious clinical findings for scabies? 

Do the results of the recent study (Misset et al., PMID 37889107) showing reduction in 28-day mortality in patients with high neutralizing antibody ti...

Is there a role for oral vancomycin in these patients, or is oral vancomycin redundant if other routes of administration are being used (i.e intracolo...

Is there a role for oral antiviral therapy alone (as opposed to induction with IV) and for what duration? And is there a role for ongoing suppressive ...

Especially in light of the results of the randomized clinical trial published on 8/2024 in Jama Internal Medicine by Hayward et al., PMID 38587819.

Assuming patient already received an initial course of antibiotic treatment in response to a positive urine culture during routine screening early in ...

Is there a role for booster vaccination and if so, how do you approach the timing when a patient is already on a biologic for immunosuppression? 

Since the COVID-19 pandemic, increasingly we see management of acute cholecystitis with cholecystostomy tubes as opposed to surgery, even amongst pati...

If yes, would you go with Zidovudine monotherapy versus combining with interferon-alpha? And what would be the preferred dose and duration? 

How do you approach ongoing screening for TB in patients with history of treated latent TB, but have ongoing use of DMARDs and/or biologics given quan...

At the time of count recovery or do you continue it throughout induction and consolidation?

Data on the role of steroids in HIV negative patients with PJP has been conflicting.

E.g., for a patient with myeloma, s/p induction therapy, and high-dose chemotherapy, followed by autologous rescue with inappropriate antibody respons...

Assuming no symptoms of TB, should patients be treated for latent TB prior to starting TNF inhibitors or other immunosuppressive agents?

What’s your threshold to get the three AFBs and place the patient in airborne isolation?

How do you approach which risk to accept given that steroids have evidence for use in COVID-19 while is suggestion for harm in using steroids in influ...

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

Do you recommend any changes to their personal hygiene practices? or changes to their environment?

Infection is not part of the criteria for starting treatment both in UpToDate and in NCCN guidelines. 

Hepatitis screening labs revealing Hep B ag and core positivity with positive PCR

Would you switch to itraconazole or perform fungal cultures? When would you consider repeating the course of treatment? 

Does treatment with B-cell depletion and/or negative anti-spike antibody status despite COVID mRNA vaccination influence your decision?

Can experts comment on fungal pneumonia risk with individual BTK inhibitors as seen in ELEVATE-RR and whether this impacts their management decisions?

Does your recommendation differ between autologous and allogeneic transplants? Does your recommendation differ in allogeneic transplant recipients wh...

Is it at neutrophil recovery, at documentation of CR on bone marrow biopsy, or is there a different point in time?


Papers discussed in this category


The New England journal of medicine, 2007-01-25

Arthritis Rheumatol, 2016 Jan

Arthritis care & research, 2012-05

Arthritis care & research, 2017-03

Clin Exp Dermatol, 2018 May 24

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2008-10

Clin Rheumatol, 2006 Dec 21

Rheumatol Int, 2020 Sep 18

N Engl J Med,

Mediterr J Rheumatol, 2020 Jun 11

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011-03

Ann Rheum Dis, 2019 Aug 14

Seminars in hematology, 2013-07

Neurology, 2020 Jul 29

Cells, 2018 Dec 28

Arthritis Rheum,

Ann Oncol, 2021 Mar 18

J Clin Oncol, 2021 Jul 26

Journal of neurovirology, 2018-06

Lancet Oncol, 2019 Oct 23

Arthritis Care Res (Hoboken), 2021 Jul

Clin Liver Dis (Hoboken), 2018 Aug 22

Scientific reports, 2017 Aug 10

Clin Microbiol Infect, 2018 Feb 07

Urology, 1982-09

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009-03

Clin Infect Dis, 2005 Jan 21

Pediatr Transplant, 2014 Sep 08

J Clin Oncol, 2021 Apr 30

Pediatr Infect Dis J, 2014 Nov

Bone Marrow Transplant, 2006 Mar

Perit Dial Int, 2022 Mar

PET Clin, 2020 Feb 11

Rheumatology (Oxford), 2022 Jul 22

The Journal of thoracic and cardiovascular surgery, 2017-12

Tex Heart Inst J, 2022 Nov 1

Circulation, 2020 Dec 17

Catheter Cardiovasc Interv, 2022 Jul 26

Multimed Man Cardiothorac Surg, 2020 Sep 25

JACC Case Rep, 2022 May 04

Circulation, 2015 Sep 15

Arthritis & rheumatology (Hoboken, N.J.), 2017-10

Ann Am Thorac Soc, 2017 May

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-06-01

Human vaccines & immunotherapeutics, 2017 Feb

Blood, 2020 Jun 18

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019-01-18

The New England journal of medicine, 2022 Mar 24

The Cochrane database of systematic reviews, 2018 Jul 24

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Jul 05

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 2021 Jul 23

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Sep 21

Journal of the Pediatric Infectious Diseases Society, 2024 Jan 03

The Journal of infectious diseases, 2022 May 04

Arthritis Care Res (Hoboken), 2016 Jan

Alimentary pharmacology & therapeutics, 2022 May 20

Curr Opin Infect Dis, 2023 Aug 1

JAMA, 2023 Jul 03

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017-11-29

Annual review of medicine, 2022 Nov 04

The Annals of thoracic surgery, 2017 Feb 04

European heart journal, 2023 Oct 14

The Annals of thoracic surgery, 2016-06

JAMA network open, 2022 Dec 01

International journal of antimicrobial agents, 2023 Jun 08

Pharmacy (Basel, Switzerland), 2023 Nov 20

International journal of antimicrobial agents, 2023 May 07

JAMA network open, 2024 Jan 02

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2023 Nov 24

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2023 Oct 26

EClinicalMedicine, 2022 Dec 01

Journal of clinical pharmacy and therapeutics, 2020 Sep 27

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019 Sep 13

European heart journal, 2023 Oct 25

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2023 May 11

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Jul 26

Infectious diseases and therapy, 2022 May 03

American journal of respiratory and critical care medicine, 2019 Oct 01

The New England journal of medicine, 2023 Apr 06

The Journal of antimicrobial chemotherapy, 2021 Jun 18

Sexually transmitted diseases, 1993 Nov-Dec

Medicine, 2014 Oct

Arthritis and rheumatism, 2013-07

Rheumatology international, 2011 Feb 23

Arthritis & rheumatology (Hoboken, N.J.), 2023 Jun 01

Arthritis care & research, 2016 Jan

Lupus, 2014 Feb 06

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009-07-01

Journal of medical case reports, 2014 Mar 04

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-12

The Lancet. Oncology, 2022 Mar 10

Journal of translational internal medicine, 2019 Dec 31

Journal of oncology practice, 2018-09-04

Leukemia & lymphoma, 2022 Mar 15

Hematology. American Society of Hematology. Education Program, 2020 Dec 04

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Sep 18

Infection control and hospital epidemiology, 2018-02

Antimicrobial stewardship & healthcare epidemiology : ASHE, 2021 Oct 21

American journal of infection control, 2023 Feb 01

Current opinion in rheumatology, 2018 Jul

European journal of medical research, 2009 Dec 07

Annals of the rheumatic diseases, 2018 Jun 27

The Lancet. Infectious diseases, 2024 Jan 17

JAMA ophthalmology, 2017 Dec 01

Journal of the American College of Cardiology, 2023 Jan 31

JACC. Cardiovascular interventions, 2022 Jun 13

JACC. Cardiovascular imaging, 2017 Aug 16

The New England journal of medicine, 2018 Aug 28

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Sep 11

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015-08-01

N Engl J Med, 2023 Mar 21

Journal of ophthalmic inflammation and infection, 2015-12

JAMA ophthalmology, 2024 Jan 01

Investigative ophthalmology & visual science, 2016 Feb

Ophthalmology. Retina, 2019 Mar 21

Retina (Philadelphia, Pa.), 2021 Feb 01

Archives of ophthalmology (Chicago, Ill. : 1960), 1995 Dec

The New England journal of medicine, 2024 Apr 04

The Journal of infectious diseases, 1980 Mar

Antimicrobial agents and chemotherapy, 1976 Sep

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2020 May 08

The Lancet. Infectious diseases, 2020 Dec 14

Open forum infectious diseases, 2023 Nov 24

The American journal of medicine, 1992-11

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017 Oct 30

Open forum infectious diseases, 2024 Mar 13

Circulation, 2008 Jun 09

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 1999 May-Jun

Nephrology (Carlton, Vic.), 2004 Jun

International ophthalmology clinics, 2022 Apr 01

Clinical ophthalmology (Auckland, N.Z.), 2020 Jul 08

Retinal cases & brief reports, 2022 Nov 01

Open forum infectious diseases, 2024 May 02

Lancet (London, England), 2021 Mar 27

Lancet (London, England), 2021 Mar 27

World journal of urology, 2013 Apr 30

JAMA internal medicine, 2024 Apr 08

The Cochrane database of systematic reviews, 2022 Aug 30

JAMA internal medicine, 2024 May 13

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019-05-30

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Aug 22

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Oct 23

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Aug 22

BMJ open, 2023 Sep 13

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019 Jun 27

The Annals of pharmacotherapy, 2023 Mar 22

Diagnostic microbiology and infectious disease, 2021 Jul 24

Open forum infectious diseases, 2023 Feb 02

Infection & chemotherapy, 2021 Jun

Retina (Philadelphia, Pa.), 2014 Sep

Eye (London, England), 2017 Jun 16

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006-07-15

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021 Jul 22

Antimicrobial agents and chemotherapy, 2023 Jul 05

The Lancet. Neurology, 2009-08

The Journal of infection, 2011-11

Alimentary pharmacology & therapeutics, 2006 Nov 15

Journal of tropical medicine, 2017 Feb 26