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Do you provide prophylactic anticoagulation with abemaciclib in the adjuvant setting given known thrombosis risk?

Would you offer it to a woman with a history of a provoked DVT?
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How do you take thrombotic risk into account when prescribing abemaciclib?

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1 Answer
Mednet Member
Mednet Member
Medical Oncology · University of Vermont Cancer Center
Answered on

I don’t generally recommend prophylactic anticoagulation with abema, either in the adjuvant or metastatic setting. There does appear to be a small, but real, incidence of thrombosis associated with abema, as well as the other CDK 4/6 inhibitors. While this risk is quite uncommon, it is important cer...

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