Do you recommend adjuvant chemotherapy in a patient with node positive gastric adenocarcinoma with mixed dMMR/MSI histology?
No preop therapy; dMMR in poorly cohesive and mucinous carcinoma component, pMMR in tubular adenocarcinoma component
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What adjuvant therapy would you recommend for a patient with a mixed dMMR and pMMR lymph node positive gastric cancer, who has undergone upfront surgery?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Memorial Sloan Kettering Cancer Center
Answered on
Well, this is certainly a situation where treatment decisions are completely unburdened by data and one could do virtually anything, from observation to immunotherapy plus chemotherapy.
A more straightforward version of this scenario is if the patient has a fully resected node-positive dMMR/MSI gastr...
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