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Do you recommend adjuvant radiation therapy for resected spine metastases in NSCLC with targetable mutations?

For example, EGFR-mutated de novo metastatic disease, do you offer adjuvant RT vs observation with targeted therapy alone?
1 Answer
Mednet Member
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Radiation Oncology · Mayo Clinic Florida
Answered on

I would offer adjuvant RT. We have no data to guide us on whether targeted therapy alone would suffice. Moreover, given that the patient had resection, most likely there was some level of cord compression involved. Would hate for that to happen again after resection with suboptimal adjuvant therapy....

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