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Do you recommend adjuvant RT for positive margins of dermatofibrosarcoma protuberans?

Would you change your management based on location, such as a sensitive area like the groin? What volumes do you recommend? Does age influence your choice?
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on

The combination of surgery and radiation results in excellent local control for DFSP: Castle et al., PMID 23628134.

Radiation is, of course, likely especially valuable when margins are less than secure. The above paper describes dose and volume considerations.

However, it's a risk/benefit discussion. Can this tumor be re-resected for R0 margins? That is usually preferable to RT. Anatomic sensitivity cuts both ways - radiation may be more morbid, but how surgically salvageable is the location?

If t...

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Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on

Yes, yes, and yes! 3 too many words!

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