Do you recommend Alpha Lipoic Acid to patients with diabetic polyneuropathy?
Answer from: at Academic Institution
Yes, because a few randomized studies have shown (small in my opinion) a positive effect on sensory symptoms and possibly other outcome measures like NIS score. I tell my patients that this is not a "cure" for diabetic neuropathy, but it may have a small benefit for positive sensory symptoms as an a...
Recommend is a strong word. I mention it to my patients as there's some 'evidence' supporting it. It has minimal side effects and virtually no risk, so it's worth a try. However, it's important to note that very few of my patients report any benefit from it.
I recommend ALA 600 mg daily or 300 mg BID to all my patients with diabetic polyneuropathy. Not only does it help with neuropathic pain, as cited by Dr. @Manousakis, but there is data to support that it may help with glucose control.
Comments
at PeaceHealth How about using quercetin for polyneuropathy?
Although ALA 600 mg daily may lack abundant potency, most patients will achieve enough relief that they prefer to continue this safe treatment long-term.Also see Bönhof et al., PMID 30256929.
For patients who prefer natural or alternative treatments or after chemotherapy, I usually recommend:
B Complex
CoQ10
Vitamin D
Magnesium
Acetyl Carnitine
Lipoic Acid (comes in different formulas)
I've been encountering more patients with B1 deficiency during my assessments. If a B1 defic...
Comments
at Harvard Medical School I would avoid B complex. As someone who has come a...