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Do you recommend avoiding combination vancomycin and piperacillin-tazobactam in patients with acute kidney injury?

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Do you recommend avoiding the combination of vancomycin and piperacillin-tazobactam in patients with acute kidney injury?

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2 Answers
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Nephrology · University Of California San Francisco Medical Center At Parnassus
Answered on

Personally, I don't think the risk is that high and I won't necessarily recommend against it. If a patient develops worse renal function while on the drugs though, I would have a low threshold of switching to something different. I would also try to avoid vancomycin levels over 30.

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Mednet Member
Mednet MemberInvited Expert
Nephrology · Rush Medical College
Answered on

No, I think that is taking an association a bit too far for me. But I could easily be wrong.

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