Do you recommend CDK4/6 inhibitor, radiotherapy, or both following surgery for a pathologic fracture from HR+ breast cancer?
Has anyone omitted post path fracture radiation of pelvis/long bone in favor of starting endocrine treatment first? Or would one omit RT and start a CDK 4/6 inhibitor? Or would it be reasonable to give concurrent CDK 4/6 inhibitor with xrt?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
The goal of therapy is to help control pain and enhance healing. Post-op RT is routine with the most common dose used by us being 20 Gy in 5. It’s reasonable to do with concurrent CDK4/6 inhibitor.
Join for free or sign in to see the full answer