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Do you recommend checking both TSI and TBII antibodies for Graves' disease diagnosis and monitoring?

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What antibody tests do you order for patients presenting with hyperthyroidism?

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1 Answer
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Endocrinology · Johns Hopkins Outpatient Endocrinology
Answered on

The two assays correlate with one another to a great degree, but they are not identical. The TRAb or TBII test measures all antibodies directed against the TSH receptor that could be stimulatory, neutral, or blocking. The TSI test only measures stimulatory antibodies, and is therefore clinically mor...

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