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Do you recommend neoadjuvant and concurrent ADT vs concurrent ADT for salvage post prostatectomy radiation?

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2 Answers
Mednet Member
Mednet Member
Radiation Oncology · Cancer Specialists of North Florida

I do both neoadjuvant and concurrent. The strategy used is typically dictated by patient schedule/convenience.

While GETUG-AFU 16 used a concurrent approach, SPPORT utilized a 2-month neoadjuvant strategy for ADT.

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Mednet Member
Mednet Member
Radiation Oncology · UPMC Hillman Cancer Center

I do concurrent. In GETUG-AFU 16, goserelin was administered on day 1 of radiotherapy and then 3 months later for a 6-month course. Unsure what the biological rationale would be to start ADT prior to radiation in the post-prostatectomy setting.

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