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Do you recommend prescribing Pneumocystis jiroveci pneumonia (PJP) prophylaxis for a patient with membranous glomerulonephritis on rituximab?

If so, how long would you continue prophylaxis?
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In which of the following clinical scenarios do you prescribe PJP prophylaxis in patients with membranous nephropathy?

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1 Answer
Mednet Member
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Nephrology · Johns Hopkins University
Answered on · Updated on

In general, I don't use Pneumocystis jirovecii pneumonia prophylaxis (PJP PPx) for patients with membranous nephropathy (MN) who have only received rituximab (RTX), unless they have also received high-dose glucocorticoids (GC) or cyclophosphamide (CYC). I usually give PJP PPx when patients receive h...

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