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Do you recommend surveillance MRI for patients with MOGAD?

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Do you recommend surveillance MRI for patients with MOGAD?

8 physicians have voted

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2 Answers
Mednet MemberInvited Expert
Neurology · University of Ottawa
Answered on

I do not recommend regular surveillance MRI for all patients. It really depends on the case as some MOGAD patients are very stable and don't even require treatment, whereas others can be quite aggressive and resistant to all treatments. The field is still emerging and our understanding of silent disease with MOGAD is poor. Emerging is the serum biomarker neurofilament light chain, which appears quite sensitive, picking up new MOGAD activity and is a lot easier and cheaper than repeated MRI scans...

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Mednet MemberInvited Expert
Neurology · Icahn School of Medicine at Mount Sinai
Answered on

Silent lesions in MOGAD are quite unusual (<6% per one source). Therefore, there is little utility to routine MRI surveillance in patients with MOGAD.

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