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Do you recommend the use of GLP 1 R agonist therapy for obese women with PCOS who are actively trying to conceive?

Dao et al., PMID 38663923
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Do you recommend the use of GLP-1 receptor agonist therapy for obese women with PCOS who are actively trying to conceive?

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2 Answers
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Endocrinology · Brigham And Womens Hospital Endocrinology
Answered on

This is a very relevant question. GLP 1 RA therapy is recommended by the recently published International Consensus Guideline in Management of PCOS for assistance with weight loss in combination with lifestyle modification (Teede et al., PMID 37580314). The guideline states that this should be done ...

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Mednet Member
Mednet MemberInvited Expert
Endocrinology · Emory University School of Medicine
Answered on

I will often use GLP1RA to help with weight loss in women with PCOS, with the added benefit of improving menstrual function and possible ease of conception down the road. However, I am clear that they should not be actively trying for pregnancy as we do not have sufficient safety data. When they hav...

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