Do you require an ECG to assess the QTc interval before administering ondansetron to a hospitalized patient without a known cardiac history or QT-prolonging medications?

There is a nice "Things We Do For No Reason" article in Journal of Hospital Medicine on this: "Hospitalists need not order an initial and subsequent ECGs when administering standard doses of intravenous ondansetron for patients without significant risk factors for QTc prolongation. To assess risk fa...

I do not typically require an ECG to start ondansetron in a patient without cardiac abnormalities or other QT-prolonging medications. I think my threshold for doing an ECG before starting this would be only if the patient had some predisposing factors to QT prolongation or arrhythmia, such as electr...