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Do you routinely check digoxin levels, and if so, when would you consider using Digibind in chronic digoxin use patients?

Is your pattern for drug monitoring different if digoxin is being given for afib vs HFrEF?
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When do you use digoxin for the management of atrial fibrillation?

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3 Answers
Mednet Member
Mednet MemberInvited Expert
Cardiology · Penn Heart And Vascular Center
Answered on

The subanalysis of the DIG trial gave some insight into the value of keeping digoxin levels below 1.0. If HF patients, I tend to look at the levels for that reason.

I rarely use digoxin for AF as there is little evidence of benefit with some evidence of harm.

Re: use of digibind, I limit this if t...

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Mednet Member
Mednet Member
Cardiology · Dartmouth-Hitchcock Medical Center
Answered on

Digoxin levels correlate with maximum inotropic effects for CHF indication. Control of AFib is based on the toxic blocking effects of digoxin, and levels are not predictive and may, in fact, need to be much higher than "therapeutic." Digoxin toxicity is based on symptoms and not levels; therefore, D...

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Mednet Member
Mednet Member
Cardiology · WVU Heart And Vascular Institute
Answered on

I rarely use digoxin as well. I think it can be helpful in patients with HF and Afib who are not able to tolerate a beta blocker and do not have other options.

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