Do you routinely continue dual antibiotic coverage or de-escalate to monotherapy based on peritoneal fluid culture sensitivities in patients with relapsing pseudomonas aeruginosa peritoneal dialysis peritonitis after peritoneal catheter removal?

If the peritoneal dialysis catheter has been removed then I would de-escalate to monotherapy based on the fluid culture sensitivities. Monitor clinical response and obtain new fluid samples for analysis if any concern for persistent infection.

I can also depend how quickly the peritonitis got better after antibiotics initiation (or did it only improve after several days of removal of the PD catheter)!