I generally offer neo-adjuvant chemotherapy for all patients with triple negative breast cancer that are larger than 1cm. Triple negative breast cancer, metaplastic or not, is comprised of a large group of heterogenous cancers. These patients all need chemotherapy and giving it in the neoadjuvant se...

I would consider neoadjuvant chemotherapy in most triple negative breast cancers, particularly those that are T1c or higher TNM stage. I would approach metaplastic cancers, largely in a similar manner. We have interesting neoadjuvant trials including platinums and/or immune checkpoint inhibitors whi...