Do you routinely recommend prophylactic cranial irradiation for stage I small-cell lung cancers treated with lobectomy and adjuvant chemotherapy?

PCI was 'associated' with better long-term survival even in stage 1, and age and size factors do not seem to matter. However, as the information gets divided, fewer patients fall into each cohort.

A recent study published in the JCO, analyzing over 1,000 patients in the NCDB, found that thoracic radi...

Great question. While we attempt to determine the benefit of PCI in the modern MRI era for limited-stage SCLC (MAVERICK trial), for a patient in this scenario, I would present the choice of PCI or undergoing surveillance MRI every three months. However, pending the results of MAVERICK, the current s...

All physicians have their personal biases, especially evident in discussions about PCI, but it's crucial not to let these biases obscure our judgment in understanding and treating cases where different approaches might be warranted.

In the context of stage I SCLC treated with resection and adjuvant c...