Topics:
Pediatric Oncology • Myelodysplastic Syndromes • Hematology • Pediatric Hematology • Benign Hematology • Cytopenia
Do you routinely send NGS testing from bone marrow samples in patients with unexplained cytopenia or cytoses?
For instance, if clonal hematopoiesis of indeterminate potential (CHIP) suspected
Answer from: Medical Oncologist at Academic Institution
For patients with unexplained cytopenias in whom I suspect MDS or MDS/MPN, I will often obtain a broad NGS panel for myeloid malignancy gene mutations. The goal is to aid in diagnosis (and prognosis once the diagnosis is made), but I do not rely on the NGS panel alone to make the diagnosis. A bone m...
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