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What is your preferred strategy for young adults with ITP complicated by recurrent autoimmune neutropenia?
ITP is well controlled on TPO-RA, but AIN which is responsive to steroids recurs despite prior rituximab. Bone marrow biopsy normal and without evidence of large granular lymphocytic leukemia.
Do you consider MMF in addition to TPO-RA versus BTKi?
Answer from: at Community Practice
This is a great question, and I'll say that AIN can be particularly difficult to treat! I'd first ask how low the ANC is and if the patient is presenting with frequent infections/hospitalizations. If not, there may not be a need to treat the AIN (we may just be treating ourselves); oftentimes, there...
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