Do you routinely treat patients with neurosyphilis with IM penicillin for 1-3 weeks after completing a full treatment course of IV penicillin?
The same question was asked almost exactly two years ago. Repeating the same reply with minor edits:
This has been a topic of a debate among syphilis experts for decades. There are no data at all on whether there is benefit (e.g. in preventing later relapse) in adding low-dose but long-acting penici...
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I agree with everything written here by Dr. @Dr. First Last. At the risk of biasing the discussion, I'd like to add that one potential, purely logistical, system-dependent benefit of providing a dose of BPG at the end of the IV penicillin course is to create a touchpoint between a patient and the he...
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This question was addressed in an article published last year in CID: Hamill et al., PMID 37593890.
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