Do you routinely use hippocampal sparing techniques in the treatment of primary brain tumors?

The hypothesis of the hippocampus as an organ at risk centers on the exquisite radiosensitivity of neuro-regnerative stem cells located within the hippocampal dentate gyrus and important for memory formation.

Pending results from NRG CC001, a recently completed phase III trial of whole-brain radiot...

Yes, indeed we do. We routinely contour both hippocampus, using the RTOG atlas in all patients, even in those in whom we know that we will not be able to achieve sparing, primarily, to develop a robust dose-response data base. As to dosimetric constraints, there are a number of approaches; the simpl...