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Do you routinely use vasopressin in the management of RV failure leading to shock state in the absence of an obvious treatable cause such as infarction or PE?

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Do you use vasopressin in the management of RV failure leading to shock state in the absence of an obvious treatable cause such as infarction or PE?

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2 Answers
Mednet Member
Mednet Member
Pulmonology · Cedars-Sinai Medical Center
Answered on

It seems that there is a vasopressin dose-dependent effect on PA pressures. The doses we usually use for septic shock (0.03 or less) have some degree of pulmonary vasodilation (for example, Tsuneyoshi et al., PMID 11373409). Higher doses may have the opposite effect (Leather et al., PMID 12441768). ...

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Mednet Member
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Pulmonology · University of Pittsburgh School of Medicine
Answered on
I must say that I do not routinely use vasopressin for RV failure. Perhaps there is evidence supporting such a practice that I am not aware of.
I typically reserve use of vasopressin for septic shock with hypotension refractory to moderate dose norepinephrine infusion.

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