Topics:
Head and Neck Cancers • Radiation Oncology
Do you take the primary dissected site for postoperative oral cavity cancers with bony invasion to 66 Gy?
Do you take it to 66 Gy even in the situation of negative margins/resection of that region of bone? For example, if there is a focal bony invasion that has been completely resected (such as a left alveolar ridge tumor s/p left maxillectomy)? Do you limit to 60 Gy if completely resected?
Answer from: Radiation Oncologist at Academic Institution
Dr. @Eisbruch correctly addresses the nuanced indication for PORT due to bone involvement.60 Gy is embedded in the PORT culture. For at least 30 years, RTOG trials have recommended 60 Gy with an optional boost to 66 Gy for PORT, though the EORTC trial (Bernier et al., PMID 15128894) went to 66 Gy fo...
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Answer from: Radiation Oncologist at Academic Institution
While any bone invasion in oral ca is regarded T4 by AJCC, there is a substantial difference between alveolar ridge cancers involving just the cortical bone (which may frequently occur in small alveolar ridge cancers), or the medullary bone. Several studies reported that medullary, but not cortical ...
Answer from: Radiation Oncologist at Academic Institution
Margins negative 60 Gy/30 fractions