Do you treat an endometrial cancer that is microsatellite-stable but has a high TMB after progressing on platinum-based therapy with pembrolizumab?
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What tumor biomakers must be present for you to use pembrolizumab alone in an endometrial cancer that has progressed following platinum-based therapy?
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2 Answers
Mednet MemberInvited Expert
Gynecologic Oncology · Center of Hope
Answered on
Yes I would. Similarly, I would also treat a patient with advanced cervical cancer with Pembrolizumab. I have a patient with PDL1 negative, TMB-High squamous cell carcinoma of cervix. Submitted to insurance for coverage and she is approved for Carbo-Taxol-Bev-Pembro. It is absolutely worth a try and...
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Mednet Member
Gynecologic Oncology · Covenant Health
Answered on
Yes, if covered.
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