New: NCI-funded clinical trial search
Mednet Logo
CommunityNeurology

Do you typically encounter phrenic involvement in patients with CIDP?

Do you see improvement with treatment such as IVIG?
1 Answer
Mednet MemberInvited Expert
Neurology · University of Minnesota
Answered on

No. Respiratory involvement is very unusual in CIDP, unlike GBS (AIDP) where it is common. In CIDP frequency of phrenic nerve involvement is <10%, probably below 5. Of course, there are always exceptions to the rule. If the phrenic nerve is involved and the mechanism is predominantly demyelinating (conduction block) as opposed to axonal degeneration, which can be gauged by assessing the CMAP amplitude of the phrenic nerve conduction study, theoretically treatment can lead to significant improvem...

Join for free or sign in to see the full answer