I would check antiphospholipid antibodies (APLAs) in a few situations in the absence of thrombotic events: 1. In someone with other APS manifestations: Obstetrical complications (especially) APL nephropathy noted on renal bx Unexplained adrenal hemorrhage/microthrombosis Non-infectious endo...

I check APLs in all women who are planning to conceive or see me while pregnant and who have a rheumatic disease. Positivity is up to 20% in other diseases. It is difficult to tell if these are pathologic or not in non-SLE diagnoses, but seeing that APS can exist as a diagnosis on its own without a ...

I do not routinely screen for the presence of APL in all non-lupus RMD without clinical signs of APLS. My rationale is that detecting APL in these patients would not typically change the management of these individuals.There is evidence suggesting a high prevalence of APL antibodies in systemic scle...

In the absence of a clotting disorder, the presence of these antibodies is not going to change my management of the patient, but it can produce a lot of anxiety in the patient. I get many referrals of patients with positive APS antibodies that were checked for unknown reasons during the annual physi...

Drs. @Rodriguez-Pla, @Sigal, and others; one reason is that we now have new EULAR/ACR APS guidelines which help to point out the need to consider APS in non-thrombotic situations. OB complications are the most evident but there are other places where we do not want to miss. It is a great educational...

Big no. Any result gives you no clinical insight and no advance in diagnosis and nothing to treat. Meanwhile you notify someone of a serologic finding of no known clinical significance so they can use the internet to find something to worry about. So, no